Psoriasis vulgaris (PV) has also been seen in association with the SAPHO syndrome.
All the histopathological results showed neutrophil granulocyte infiltration without infection or malignant disease.One hundred and sixty-four patients suffered from pain in the anterior chest wall, followed by spine (12 in the cervical region, 36 in the thoracic region and 111 in the lumbosacral region) and peripheral joint (136 patients) involvement. One hundred and thirty-one (79.9%), 85 (51.8%), 100 (61%) and 54 (32.9%) patients took NSAIDs, CSs, DMARDs and oral bisphosphonates, respectively. SAPHO syndrome is predominant in middle-age women, characterized by dermatological and osteoarticular manifestations with unknown aetiology.CT scan and bone scintigraphy are useful for diagnosis.Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, State Key Laboratory of Medical Molecular Biology and Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, State Key Laboratory of Medical Molecular Biology and Department of Central Laboratory, Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, P. The medical data, laboratory test results and imaging were collected for all patients. One hundred and sixty-four patients (111 women and 53 men) were recruited to our cohort. Nine patients had osteoarticular symptoms without skin involvement. The aim was to assess the clinical, laboratory and radiological features of SAPHO syndrome. We recruited all patients presenting to Peking Union Medical College Hospital from 2004 to 2015 diagnosed with SAPHO syndrome.Imaging findings of ACW lesions, including osteolysis, sclerosis and hyperostosis (Fig. Spinal disorders, which mainly included vertebral lesions and paravertebral ossifications, could be detected in 79.2% (42/53) and 71.7% (38/53) patients, respectively.